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Published on: October 18, 2024
Prevalence of refractive error in Nigerian children
Steve O Adebusoye1, Oghogho Onovae2, Temiwoluwa Adebusoye2
1Department of Ophthalmology, University College Hospital, Ibadan, Nigeria.
Insights
Refractive errors affect 5.9% of Nigerian children, with higher risks for girls, older children, and urban residents. School screenings are recommended, especially for these groups, to address this public health concern.
Area of Science:
- Ophthalmology
- Public Health
- Pediatrics
Background:
- Refractive errors significantly impact children's development and education.
- Existing global data inadequately represent the prevalence in Nigerian children.
- National studies are hindered by cost and logistical challenges.
Purpose of the Study:
- To determine the pooled prevalence and patterns of refractive error among Nigerian children.
- To provide data crucial for public health interventions and policy-making in Nigeria.
- To identify demographic and geographic factors associated with refractive error in this population.
Main Methods:
- Systematic review and meta-analysis adhering to PRISMA guidelines.
- Comprehensive search of multiple databases for school-based and population-based studies.
- Inclusion of 28 studies encompassing 34,866 Nigerian children under 18 or in pre-tertiary institutions.
Main Results:
- The pooled prevalence of refractive error was 5.9% (95% CI: 3.6-8.7%), with variations based on study definitions and regions.
- Children needing screening to detect one case of refractive error was 15 (95% CI: 9-21).
- Increased odds of refractive error were observed in girls (OR: 1.3), children over 10 years (OR: 1.7), and urban residents (OR: 2.0).
Conclusions:
- The prevalence of refractive error in Nigerian children warrants targeted screening programs in schools.
- Screening efforts should prioritize urban areas and older children.
- Further research, including population-based studies and refined case definitions, is necessary to fully understand and address refractive errors in Nigerian children.
Abstract:
Refractive errors can have profound effects on children. Cost and logistics prohibit national population-based studies and global data do not accurately reflect the burden among Nigerian children. This systematic review and meta-analysis aim to provide pooled prevalence and pattern of refractive error in Nigerian children. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The protocol for this study was pre-specified and registered on the International Prospective Register of Systematic Review (registration number ID: CRD42022303419). A systematic search of PubMed, EMBASE, Scopus, CINAHL Cochrane Library, African Journal Online, and African Index Medicus databases, was done for school-based, or population-based studies on refractive error prevalence in Nigerian children younger than 18 years of age or school children in pre-tertiary institutions. Quality-effect model was used to calculate weighted prevalence, odds ratio, and corresponding 95% confidence interval. Twenty-eight school-based studies including 34,866 children were identified. No population-based studies were found. The pooled prevalence of refractive error in Nigerian children was 5.9% (3.6-8.7%) and varied between regions and with the definition of refractive error used in the studies. The number of children needed to be screened to detect one case of refractive error was 15 (9-21). The odds of refractive error was higher in girls (odds ratio: 1.3 {1.1 to 1.5}), children >10 years (odds ratio: 1.7 {1.3 to 2.2}), and urban residents (odds ratio: 2.0 {1.6 to 2.5}). The high prevalence of refractive error in Nigerian children substantiates the value of screening school children for refractive error, particularly targeting urban and older children. Research is needed to refine case definitions and improve screening protocol. Population-based studies are needed to define the prevalence of refractive error in communities. The epidemiologic and methodological challenges in conducting prevalence reviews is discussed.
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