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Synthesis and biological evaluation of oleanolic acid derivatives with electrophilic warheads as antitumor agents

Shisheng Wang1,2, Dongxue Yang1, Xiaorui Li3

  • 1Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.

Future Medicinal Chemistry
|May 25, 2023
PubMed

Keywords:
antitumorapoptosis inductionelectrophilic warheadsferroptosis inductioninhibition of Akt/mTOR pathwayinhibition of GPX4oleanolic acid derivatives

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