Related Experiment Video

Updated: Jul 29, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

11.4K

Correction to "Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors

Hailing Chen, Meimiao Zhan, Jianbo Liu

    Journal of Medicinal Chemistry
    |May 25, 2023
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
    11:09

    Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

    Published on: August 1, 2018

    10.8K
    Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
    10:58

    Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

    Published on: July 25, 2013

    17.1K

    Related Experiment Videos

    Last Updated: Jul 29, 2025

    Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
    10:33

    Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

    Published on: October 26, 2015

    11.4K
    Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
    11:09

    Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

    Published on: August 1, 2018

    10.8K
    Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
    10:58

    Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

    Published on: July 25, 2013

    17.1K

    Related Concept Videos

    Structure-Activity Relationships and Drug Design01:28

    Structure-Activity Relationships and Drug Design

    804
    Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
    SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
    804

    Articles linked to this work by shared authors, journal, and citation graph.

    Spinal cord stimulation as a novel neuromodulation strategy for enhancing language recovery in post-stroke aphasia: a hypothesis.

    Frontiers in human neuroscience·2026

    Real-World Effectiveness and Safety of Imrecoxib Across Diverse Pain Conditions: A Multicenter, Retrospective Cohort Study of 30,214 Patients.

    Drug design, development and therapy·2026

    Multi-Omics Integration and Proteomic Annotation Prioritize FAM174BAssociated Monocyte Remodeling in COPD and Lung Adenocarcinoma.

    Current cancer drug targets·2026

    Gaseous liquid nitrogen-assisted cryo-printing strategies for challenging volumetric anisotropic tissues fabrication.

    Science advances·2026

    Pharmacologic inhibition of SOX9-CDK4 by CYD-4-61 impairs gastric adenocarcinoma growth and amplifies anti-PD-1 response.

    Cancer letters·2026

    The NLRP3 inflammasome in the pathogenesis of erectile dysfunction: mechanistic insights and therapeutic potential.

    Sexual medicine reviews·2026

    Synthetic Heparan Sulfate-like Oligosaccharides as Tools to Decipher Growth Factor Recognition.

    Journal of medicinal chemistry·2026

    A Novel Trigonal Prismatic Rhenium Complex of 2-Hydroxythiobenzhydrazide as a Potent and Selective Anticancer Agent.

    Journal of medicinal chemistry·2026

    Bifunctional Ionophores for Cuproptosis Activation: Dual Targeting of Copper and Fe-S Protein Homeostasis.

    Journal of medicinal chemistry·2026

    Lead Optimization of Quinoline-Coumarin KRAS mRNA G-Quadruplex Ligands: Discovery of Non-Quaternary Ammonium Analogs as Translation Inhibitors.

    Journal of medicinal chemistry·2026

    Accurate Identification of Covalently Ligandable Cysteines Using CCSite.

    Journal of medicinal chemistry·2026

    High-Resolution Relaxometry for Fragment Screening.

    Journal of medicinal chemistry·2026

    The shelved pipeline: AI can find strategically abandoned medicines and bring them to patients.

    Drug discovery today·2026

    Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1 inhibition: Synthesis, biological evaluation, and preliminary in Vivo studies.

    Bioorganic & medicinal chemistry·2026

    Potential Relationship Between Macrophage Inflammatory Protein-1β and Diabetic Kidney Disease: A Multi-Model Study.

    International journal of general medicine·2026

    A viscosity-tunable microgel-in-sol phase for localized inner ear delivery of small hydrophilic drug.

    Materials today. Bio·2026

    Receptor-mimicking antibodies retain neutralization of recent SARS-CoV-2 variants.

    Biosafety and health·2026

    Expanding Quantitative Medicines' Reach: Systems and Methods to Enhance R&D Productivity and Decision-Making in the Agentic-Era.

    Clinical and translational science·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us