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Updated: Jul 29, 2025

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Role of open access echocardiography in detection of cardiac structural and functional abnormalities
Jason Chai1, Hasan Mohiaddin1, Amit K J Mandal1
1Department of Medicine and Cardiology, Wexham Park Hospital, Slough, UK.
Insights
Open access echocardiography detected significant heart disease in 27.3% of patients with cardiac symptoms referred by general practitioners. This approach enables early diagnosis of conditions like heart failure and valve disease, improving patient outcomes.
Area of Science:
- Cardiology
- Diagnostic Imaging
- Public Health
Background:
- Cardiac symptoms are common reasons for general practitioner (GP) referrals.
- Early detection of structural heart disease is crucial for timely intervention and improved patient outcomes.
- The role of open access echocardiography in primary care settings needs further evaluation.
Purpose of the Study:
- To determine the prevalence and incidence of significant structural heart disease in patients with cardiac symptoms referred by GPs.
- To assess the utility of open access echocardiography without prior cardiologist consultation.
- To identify the frequency of left ventricular and cardiac valve abnormalities.
Main Methods:
- A prospective study involving 488 patients referred by GPs for transthoracic echocardiography.
- Echocardiography performed within 4-6 weeks of referral via an online platform.
- Analysis focused on detecting structural abnormalities, particularly in the left ventricle and cardiac valves.
Main Results:
- 27.3% of patients exhibited at least one abnormality requiring management change.
- Heart failure with left ventricular systolic dysfunction (LVSD) was confirmed in 9% (33 new diagnoses).
- Significant cardiac valve disease was diagnosed in 8.6% (30 new diagnoses).
Conclusions:
- Major structural and functional cardiac abnormalities are prevalent in patients presenting to GPs with cardiac symptoms.
- Unrestricted open access echocardiography facilitates early detection of significant cardiac pathology.
- Timely intervention based on early diagnosis may improve cardiovascular outcomes.
Purpose:
To evaluate the prevalence and incidence of significant structural heart disease in targeted patients with cardiac symptoms referred by general practitioners (GPs) using open access echocardiography, without prior clinical evaluation by a cardiologist.
Design:
Data were derived from 488 subjects who underwent transthoracic echocardiography between January and April 2018. Patients were referred directly by GPs in East Berkshire, South England, through an online platform. Echocardiography was performed within 4-6 weeks of referral and all reports were assessed by a consultant cardiologist with expedited follow-up facilitated pro re nata. Results were analysed to determine the frequency of detection of structural abnormalities, particularly of the left ventricle and cardiac valves.
Results:
Echocardiography was prospectively performed in consecutive subjects (50% male, mean (±SD) age 68.5±22 years; 50% female; mean (±SD) 64.6 (±19.1)). At least one abnormality likely to change management was found in 133 (27.3%) of all open access echocardiograms. Clinical heart failure with left ventricular systolic dysfunction (LVSD) and diastolic dysfunction was confirmed in 46 (9%) and 69 (14%), respectively. Of the 46 patients with LVSD, 33 were new diagnoses. Significant cardiac valve disease was found in 42 (8.6%) patients. 12 of these had known valvular disease or previous valvular surgery, and 30 were new diagnoses.
Conclusion:
Major structural and functional cardiac abnormalities are common in late middle-aged patients who present to GPs with cardiac symptoms and signs. Reported, unrestricted open access echocardiography enables early detection of significant cardiac pathology and timely intervention may improve cardiovascular outcomes.
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