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Updated: Jul 29, 2025

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Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
Published on: January 16, 2013
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Preclinical models and evaluation criteria of prostatitis
Hailan He1,2, Hui Luo1,2, Hui Xu2,3,4
1The First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Frontiers in Immunology
|May 25, 2023
Summary
Prostatitis, a common condition affecting men, can lead to pain and infertility. This review compares preclinical models to advance research on chronic non-bacterial prostatitis.
Area of Science:
- Urology
- Experimental Medicine
Background:
- Prostatitis is a prevalent urological condition impacting nearly half of men.
- It can cause symptoms like pelvic pain, frequent urination, and infertility.
- Chronic non-bacterial prostatitis has a complex pathogenesis, posing research challenges.
Purpose of the Study:
- To review and compare preclinical models for prostatitis research.
- To evaluate models based on methods, success rates, and applicability.
- To advance the understanding and basic research of prostatitis.
Main Methods:
- Literature review of experimental prostatitis models.
- Comparative analysis of model methodologies.
- Assessment of model success rates and evaluation criteria.
Main Results:
- Identification of various preclinical prostatitis models.
- Comparison of their strengths and limitations.
- Evaluation of their suitability for different research applications.
Conclusions:
- Preclinical models are crucial for studying prostatitis.
- Selecting the appropriate model is key for successful research.
- This review provides a guide for choosing and utilizing prostatitis models.

