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Updated: Jul 29, 2025
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
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Amsler Grid Versus 10-2 Test in Primary Open Angle Glaucoma
Temitope Mariam Gbadegesin1, Olusola Olawoye2, Tarela Frederick Sarimiye2
1Eleta Eye Institute, Eleta, Ibadan, Nigeria.
Journal of the West African College of Surgeons
|May 25, 2023
Summary
The Amsler grid shows low sensitivity for detecting early primary open angle glaucoma (POAG) but can help identify severe POAG in resource-limited areas. This tool aids in the early detection of glaucoma, a leading cause of irreversible blindness.
Area of Science:
- Ophthalmology
- Public Health
- Medical Diagnostics
Background:
- Glaucoma is a primary cause of irreversible blindness globally, necessitating early detection and treatment.
- Resource-limited settings face challenges with cost-effective glaucoma detection equipment.
- A simple, affordable tool is needed for community-based glaucoma screening.
Purpose of the Study:
- To evaluate the Amsler grid's accuracy in detecting central visual field defects in primary open angle glaucoma (POAG).
- To assess the Amsler grid's utility as a screening tool in resource-scarce environments.
Main Methods:
- A cross-sectional study involving 150 glaucoma patients in Nigeria.
- Comparison of Amsler grid results with standard 24-2 and 10-2 central visual field (CVF) tests.
- POAG severity classification using Hodapp-Parrish-Anderson criteria.
Main Results:
- The Amsler grid demonstrated low sensitivity (49.5%) but high specificity (95.9%) compared to 10-2 CVF.
- Sensitivity significantly increased with POAG severity: 20.0% (mild), 31.0% (moderate), and 76.6% (severe).
- Amsler grid scotoma area correlated with 10-2 Mean Deviation (MD), Scotoma Extent (SE), and Scotoma Mean Depth (SMD).
Conclusions:
- The Amsler grid is not sensitive enough for mild-to-moderate POAG detection.
- It can serve as an adjunctive tool for identifying severe POAG in community settings by primary eye care providers.
- The Amsler grid's effectiveness is limited but potentially valuable in resource-constrained areas for advanced glaucoma cases.
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