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Updated: Jul 29, 2025

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
COVID-19 increases a person's risk of cardiovascular problems: how common is chronic heart failure in SARS-CoV-2
1Pharmacy Department, All Africa Leprosy, Tuberculosis and Rehabilitation Training Centre, Zenebework, Kolfe Keranio, Addis Ababa, Ethiopia.
Insights
Coronavirus disease 2019 (COVID-19) can cause severe heart problems. This case report highlights enoxaparin
Area of Science:
- Cardiology and Infectious Diseases
- Myocardial Injury and Cardiac Failure in COVID-19
Background:
- Coronavirus disease 2019 (COVID-19) infection commonly affects the lungs but can lead to life-threatening cardiac complications, including heart failure.
- Patients with pre-existing chronic heart failure are more susceptible to severe outcomes from COVID-19 due to diminished cardiopulmonary reserve and increased risk of myocardial injury.
Purpose of the Study:
- To present a case of COVID-19 presenting with acute heart failure and discuss the potential dual benefits of enoxaparin.
- To explore the role of enoxaparin in managing COVID-19 patients with cardiac compromise.
Main Methods:
- A case presentation of a 60-year-old female admitted with symptoms suggestive of heart failure and COVID-19.
- Echocardiogram to assess left ventricular ejection fraction.
- COVID-19 testing via reverse transcription polymerase chain reaction (RT-PCR).
- Treatment with subcutaneous enoxaparin for deep venous thromboembolism prophylaxis.
Main Results:
- The patient tested positive for COVID-19 and presented with symptoms including muscular weakness, shortness of breath, and reduced ejection fraction (43%).
- Enoxaparin was administered for deep venous thromboembolism prophylaxis.
Conclusions:
- COVID-19 infection can precipitate cardiac failure and arrhythmias, potentially causing direct myocardial damage.
- Enoxaparin demonstrated potential dual benefits by reducing venous thromboembolism risk in hospitalized COVID-19 patients and potentially preventing cardiac ischemia in myocardial infarction.
Abstract:
The coronavirus disease of 2019 (COVID-19) infection typically affects the lungs but can also cause life-threatening heart issues. Heart failure is a common condition that can occur either with an existing heart condition or de novo as part of the clinical course of COVID-19.
Case Presentation:
On 11 October 2022, a 60-year-old middle-aged black African woman widow was admitted with a history of muscular weakness for 2 days, a lack of appetite, and occasional vomiting for 1 day. She arrived at the emergency room after complaining for 2 days of peeing less than usual, a fast heartbeat, swelling in the feet, pink blood-tinged mucus, fever, headache, dehydration, a nonproductive cough, and shortness of breath. The left ventricular ejection fraction was 43% on the echocardiogram. Routine reverse transcription polymerase chain reaction testing was performed in the emergency room; she tested COVID-19 positive. To treat her proven COVID-19 infection, she received subcutaneous enoxaparin 80 mg every 12 h as prophylaxis for deep venous thromboembolism.
Clinical Discussion:
A COVID-19 infection can induce cardiac failure and arrhythmias, as well as cause direct harm to the heart. This study explains how enoxaparin has dual benefits in this case report: it reduces the risk of venous thromboembolism in the COVID-19 hospitalized case and prevents death and cardiac ischemia in myocardial infarction.
Conclusion:
Higher mortality and more frequent acute decompensation may be caused by the capacity of severe acute respiratory syndrome associated coronavirus 2 to cause myocardial injury, as well as by patients with chronic heart failure's lower baseline features, decreased cardiopulmonary reserve, and susceptibility for myocardial injury.
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