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Updated: Jul 29, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
Published on: June 14, 2022
Early Detection of Chikungunya Virus Utilizing the Surface Plasmon Resonance Comprising a Silver-Silicon-PtSe2
Thangjam Iboyaima Singh1, Pawan Singh1, Bhishma Karki2,3,4
1Department of Physics, Himalayiya University, Doiwala, Dehradun, Uttarakhand 248140 India.
Abstract:
The sensing performance parameters of the SPR sensors are sensitivity, detection accuracy, the figure of merit (FOM), and full-width half maximum (FWHM), and it has been discussed with refractive indexes of analyte 1.33, 1.35, 1.38, and 1.39. In this, we proposed a multilayer structure comprising nanofilms of Ag, Silicon, and PtSe2 for the early diagnosis of chikungunya virus. The suggested sensor structure consists of a BK7 (borosilicate crown) coupling prism over which the nanofilm of silver metal is present. The layer thicknesses and the number of silicon and PtSe2 sheets are optimized for high performance. At the operating wavelength of 633 nm, a Kretschmann-based SPR sensor has been proposed, which gives the highest sensitivity of 287.3 Deg/RIU. The principle of attenuated total reflection has been employed for the performance analysis of the sensor.
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