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Updated: Jul 29, 2025

Diagonal Method to Measure Synergy Among Any Number of Drugs
Published on: June 21, 2018
[Interactions between drugs, environment and health: a new challenge for epidemiology.]
Ursula Kirchmayer1, Elisabetta Poluzzi2, Francesco Barone-Adesi3
1Dipartimento di Epidemiologia Asl Roma 1, Ssr Lazio.
Abstract:
Traditionally, the effects of drugs and of environmental factors on health have been studied independently. Recently, several research groups have started to broaden the view and consider potential overlaps and interactions between environmental exposures and drug use. In Italy, regardless the strong competencies in environmental and pharmaco-epidemiology and the availability of detailed data, to date research in the fields of pharmacoepidemiology and environmental epidemiology is mainly being conducted in silos, but time has come to dedicate attention to possible convergence and integration between the two disciplines. The present contribution aims at introducing the topic and highlighting potential for opportunities in research by illustrating some examples.
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