[Multicentric B cell lymphoma in an 8-week-old calf]
Marie Frischkorn1, Michael Fortelny1, Malgorzata Ciurkiewicz2
1Praxis und Klinik für Rinder, Dr. Doris Jahn-Falk, Dr. Konrad Bierhorst, Hofbieber.
Summary
This case report details a juvenile sporadic bovine lymphoma in an 8-week-old calf. The condition presented atypically with enlarged lymph nodes and rapidly progressed, leading to the calf
Area of Science:
- Veterinary Pathology
- Bovine Oncology
- Immunohistochemistry
Context:
- Sporadic bovine leukosis (SBL) is a rare lymphoproliferative disorder in cattle.
- Juvenile forms of SBL are particularly uncommon and present diagnostic challenges.
- This case involves a young cross-breed calf with unusual clinical signs.
Purpose:
- To document and analyze a case of sporadic bovine leukosis in a young calf.
- To investigate the clinical, hematological, sonographic, and pathological features of the disease.
- To differentiate SBL from enzootic bovine leukosis (EBL) using diagnostic techniques.
Summary:
- An 8-week-old calf presented with suspected pulmonary infection but showed generalized lymphadenopathy.
- Hematological and sonographic findings suggested SBL; post-mortem examination revealed multicentric B-cell lymphoma.
- Immunohistochemistry confirmed B-cell markers (Pax 5, CD20), and virology excluded EBL, indicating a juvenile SBL form.
Impact:
- Highlights the importance of considering SBL in young cattle with lymphadenopathy.
- Contributes to understanding the diverse presentations of sporadic bovine lymphoma.
- Provides diagnostic insights for differentiating SBL from EBL in challenging cases.
