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Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
07:56

Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis

Published on: May 5, 2023

453

Clinical characteristics of COVID-19 associated vasculopathic diseases

Thiemo Greistorfer1, Philipp Jud2

  • 1Division of Angiology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz, 8036, Austria.

Thrombosis Journal
|May 25, 2023
PubMed

Insights

Coronavirus disease 19 (COVID-19) impacts the cardiovascular system, causing unique vasculopathies. This review compares COVID-19-associated vascular issues with non-COVID-19 conditions.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Vascular Biology

Background:

  • COVID-19 affects multiple organ systems, including the cardiovascular system.
  • COVID-19-associated vasculopathies, encompassing thromboembolic events and inflammatory changes, are increasingly recognized.
  • These vascular conditions may differ from non-COVID-19 vasculopathies in presentation and outcomes.

Purpose of the Study:

  • To review the epidemiology, clinical features, diagnostics, and outcomes of COVID-19-associated thromboembolic events and inflammatory vasculopathies.
  • To compare and contrast COVID-19-associated vasculopathies with their non-COVID-19 counterparts.

Main Methods:

  • Literature review focusing on COVID-19-associated vasculopathies.
  • Comparative analysis of COVID-19 and non-COVID-19 cohorts regarding vascular events.
  • Synthesis of data on epidemiology, clinical characteristics, diagnosis, treatment, and outcomes.

Main Results:

  • COVID-19 is linked to diverse vasculopathies, including venous and arterial thromboembolism.
  • Inflammatory vasculopathic changes are frequently observed in COVID-19 patients.
  • COVID-19-associated vasculopathies exhibit distinct epidemiological and clinical profiles compared to non-COVID-19 vasculopathies.

Conclusions:

  • COVID-19 poses significant risks for cardiovascular complications, particularly vasculopathies.
  • Understanding the unique aspects of COVID-19-associated vasculopathies is crucial for effective management.
  • Further research is warranted to elucidate the mechanisms and optimize treatment strategies.

Keywords:
Arterial thromboembolismCOVID-19VasculitisVenous thromboembolism

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