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Myringoplasty for Eosinophilic Otitis Media.
Saori Kikuchi1, Saeko Yoshida1, Tomonori Sugiyama1
1Department of Otolaryngology/Deafness and Middle Ear Surgicenter, Tokyo Kita Medical Center, 4-17-56, Akabanedai, Kita-ku, Tokyo 115-0053, Japan.
Summary
Myringoplasty for eosinophilic otitis media (EOM) with perforated eardrums is safe and effective when combined with biologics. This approach improves hearing and reduces middle ear effusion recurrence, challenging previous surgical contraindications.
Area of Science:
- Otolaryngology
- Allergy and Immunology
- Surgical Innovation
Background:
- Eosinophilic otitis media (EOM) with perforated eardrums has traditionally been a contraindication for middle ear surgery due to risks.
- Myringoplasty, a less invasive surgical option, was investigated for its efficacy in EOM patients.
Purpose of the Study:
- To evaluate the surgical outcomes of myringoplasty in patients with EOM and perforated eardrums who were treated with biological drugs (biologics).
Main Methods:
- A retrospective chart review was conducted at a tertiary referral center.
- Nine ears of seven patients with EOM and perforated eardrums, treated with add-on biologics and myringoplasty, were compared to 17 ears of 11 patients treated with myringoplasty alone.
Main Results:
- Biologics significantly decreased EOM severity scores, while myringoplasty did not.
- The biologics group showed significant improvement in air conduction hearing levels.
- Recurrence of middle ear effusion was lower in the biologics group (1/9 ears) compared to the control group (10/17 ears).
Conclusions:
- This study is the first to report successful surgical interventions for EOM using add-on biologics.
- Myringoplasty, in conjunction with biologics, is indicated for EOM patients with perforated eardrums to enhance hearing and prevent effusion recurrence.
