Related Experiment Video

Updated: Jul 29, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:15

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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Clinical Features, Socioeconomic Status, Management, and Outcomes of Acute Heart Failure: PEACE MENA Registry Phase I

Hanan AlBackr1, Khalid F Alhabib1, Kadhim Sulaiman2

  • 1Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud Medical City, King Saud University, Riyadh, Saudi Arabia.

Current Vascular Pharmacology
|May 26, 2023
PubMed

Insights

Patients in Arab countries with acute heart failure (AHF) often have multiple risk factors and low socioeconomic status. Lower income was linked to more hospitalizations, highlighting disparities in AHF care.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Acute heart failure (AHF) presents a significant health challenge globally, particularly in diverse regions like the Middle East and North Africa (MENA).
  • Understanding the specific characteristics and outcomes of AHF patients in the MENA region is crucial for targeted interventions and improved healthcare strategies.

Purpose of the Study:

  • To report the baseline characteristics and outcomes of hospitalized patients with AHF enrolled in the PEACE MENA registry.
  • To analyze the impact of socioeconomic factors on AHF patient outcomes within the Arab countries.

Main Methods:

  • Prospective, multi-center, multi-country registry (PEACE MENA) involving patients hospitalized with AHF.
  • Collection of data on clinical characteristics, echocardiography, B-type natriuretic peptide (BNP) levels, socioeconomic status, management strategies, and 1-month and 1-year outcomes.

Main Results:

  • 1258 adult AHF patients from 16 Arab countries were recruited between April 2019 and June 2020. Mean age was 63.3 years, with 56.8% males. High prevalence of comorbidities: 55% diabetes, 67% hypertension. 55% had heart failure with reduced ejection fraction (HFrEF), 19% had heart failure with preserved ejection fraction (HFpEF).
  • At 1 year, 3.6% received heart failure devices and 7.3% used angiotensin receptor neprilysin inhibitors. 1-month mortality was 4.4%, and 1-year post-discharge mortality was 11.77%.
  • Lower-income patients (≤US$500/month) experienced higher 1-year heart failure hospitalization rates (45.6% vs. 29.9%, p=0.001) compared to higher-income patients, though 1-year mortality difference was not statistically significant (13.2% vs. 8.8%, p=0.059).

Conclusions:

  • AHF patients in Arab countries exhibit a substantial burden of cardiovascular risk factors, coupled with low income and limited education.
  • Significant heterogeneity exists in key performance indicators for AHF management across different Arab countries.
  • Socioeconomic status, particularly income, appears to influence hospitalization rates, underscoring the need for tailored healthcare approaches addressing socioeconomic disparities in AHF management.
Abstract

Keywords:
AHFAcute heart failureHFrEFMiddle EastNorth AfricaPEACE MENA

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