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Updated: Jul 29, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Congenital glaucoma in a tiger (Panthera tigris)
Allison E Dianis1, Chantale L Pinard1, Sara Pagliarani1
1Health Sciences Centre (Dianis, Dutton), Department of Clinical Studies (Pinard), Department of Pathobiology (Pagliarani, Susta), Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Objective:
To describe a case of congenital glaucoma in atiger (Panthera tigris).
Animal Studied:
An 8-month-old intact female tiger wasreferred for suspected glaucoma of the right eye. The right eye was buphthalmicwith moderate episcleral injection, circumferential superficial cornealneovascularization, moderate corneal edema, and a fixed dilated pupil. Tapetalreflection was absent due to a mature cataract. Rebound tonometry under generalanesthesia revealed 70 mmHg and 21 mmHg in the right and left eye, respectively.
Procedure:
A trans-conjunctival enucleation was performedand the globe was submitted for histopathology.
Results:
Histopathology revealed a thin sclera, amorphousmaterial contouring an imperforate and hypoplastic iridocorneal angle, ahypoplastic lens with severe anterior-posterior compression, subcapsularepithelial hyperplasia, and Morganian globules, and segmental moderate retinalatrophy. Periodic acid-Schiff stain highlighted segmental dilations of theDescemet's membrane. Masson trichrome stain highlighted a pre-irido collagenmembrane.
Conclusion:
The tiger's age and histopathologic findingsare consistent with congenital goniodysgenesis. This is the first known reportof congenital glaucoma in a tiger.
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