Related Experiment Video
Updated: Jun 15, 2026

Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
Published on: October 3, 2010
Pediatric Gnathic Bony and Mesenchymal Tumors
Yingci Liu1, Molly Housley Smith2, Paras B Patel3,4
1Rutgers School of Dental Medicine, Newark, NJ, USA.
This review focuses on bone pathology in the pediatric head and neck, specifically gnathic bones. It highlights the role of odontogenesis and embryological cells in disease development and emphasizes clinical and radiographic correlation for diagnosis.
Area of Science:
- Pathology
- Oral and Maxillofacial Surgery
- Pediatric Dentistry
Background:
- Bone pathology in the head and neck, particularly gnathic bones, presents unique challenges.
- Odontogenesis and embryological cell involvement contribute to disease complexity and histologic variability.
- Accurate diagnosis requires careful clinical correlation and radiographic imaging.
Purpose of the Study:
- To review bone pathologies with a predilection for the pediatric population in the craniofacial skeleton.
- To provide a foundational understanding for pathologists evaluating these lesions.
- To discuss entities relevant to pediatric gnathic bone pathology.
Main Methods:
- Literature review of pediatric craniofacial bone pathologies.
- Focus on entities with specific predilections.
- Emphasis on diagnostic correlation.
Main Results:
- Identified key factors influencing gnathic bone pathology, including odontogenesis.
- Highlighted the importance of distinguishing between various entities.
- Underscored the need for integrated diagnostic approaches.
Conclusions:
- Understanding the unique aspects of pediatric gnathic bone pathology is crucial.
- Clinical and radiographic correlation are essential for accurate diagnosis.
- This review serves as a foundational resource for pathologists.
More Related Videos
07:50Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts
Published on: May 25, 2018
08:57Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Related Concept Videos
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...