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Updated: Jul 29, 2025
08:05
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
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Liquid Embolic Agents for Endovascular Embolization: A Review.
Amrita Pal1, Jeffrey Blanzy1, Karime Jocelyn Rosas Gómez1
1Center for Interventional Biomaterials, School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA.
Gels (Basel, Switzerland)
|May 26, 2023
Summary
Liquid embolic agents are injected to treat vascular abnormalities, transforming into solid implants. This review covers their clinical and pre-clinical applications in endovascular embolization procedures.
Area of Science:
- Biomaterials Science
- Interventional Radiology
- Vascular Surgery
Background:
- Endovascular embolization (EE) is a minimally invasive technique for treating vascular abnormalities like aneurysms and arteriovenous malformations (AVMs).
- The procedure involves occluding abnormal blood vessels using biocompatible embolic agents delivered via catheter under imaging guidance.
Purpose of the Study:
- To review the use of liquid embolic agents in endovascular embolization.
- To discuss their application in various clinical scenarios and pre-clinical research.
Main Methods:
- Liquid embolic agents are injected through catheters into target vessels using X-ray angiography.
- These agents solidify in situ via polymerization, precipitation, or cross-linking.
- Both natural and synthetic polymers are employed as liquid embolic agents.
Main Results:
- Several polymers have been successfully developed for liquid embolic agents.
- Liquid embolic agents offer a versatile approach for vascular occlusion.
Conclusions:
- Liquid embolic agents are effective tools in endovascular embolization for diverse vascular conditions.
- Continued research into polymer development and application enhances treatment options.
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