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Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
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Correlation between Coronary Artery Disease with Other Arterial Systems: Similar, Albeit Separate, Underlying

Alexandru Achim1,2,3, Orsolya Ágnes Péter4, Mihai Cocoi1

  • 1Department of Cardiology, "Niculae Stancioiu" Heart Institute, University of Medicine and Pharmacy "Iuliu Hatieganu", Motilor 19-21, 400001 Cluj-Napoca, Romania.

Journal of Cardiovascular Development and Disease
|May 26, 2023
PubMed

Insights

Atherosclerosis impacts the entire arterial tree heterogeneously, with varying plaque composition and clinical outcomes. This review explores topographical interrelations of atherosclerosis across different arterial districts.

Area of Science:

  • Cardiovascular Medicine
  • Pathology
  • Vascular Biology

Background:

  • Atherosclerosis is a systemic disease affecting the entire arterial tree.
  • Plaque composition and clinical manifestations vary by location and structure.
  • Interrelations between arterial systems extend beyond shared risk factors.

Purpose of the Study:

  • To discuss the heterogeneity of atherosclerotic impairment in different arterial districts.
  • To investigate evidence on the topographical interrelations of atherosclerosis.

Main Methods:

  • Perspective review of existing literature.
  • Analysis of studies focusing on topographical relationships in atherosclerosis.

Main Results:

  • Atherosclerosis exhibits significant variability in its distribution and characteristics across different arterial systems.
  • Topographical interrelations suggest complex interactions beyond shared risk factors.

Conclusions:

  • Understanding the heterogeneity and interrelations of atherosclerosis is crucial for comprehensive disease management.
  • Further research into topographical patterns can reveal novel insights into atherosclerotic disease progression.

Keywords:
arterial treeatherosclerosiscarotid artery diseasecoronary artery diseaseperipheral artery diseasevulnerable plaque

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