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Coccidioidal Pulmonary Cavitation: A New Age.
Lovedip Kooner1,2, Augustine Munoz1,2,3, Austin Garcia1,2,3
1Department of Medicine, Division of Infectious Diseases, Kern Medical Center, Bakersfield, CA 93306, USA.
Journal of Fungi (Basel, Switzerland)
|May 26, 2023
Summary
Coccidioides fungal infections can cause lung cavities, a condition often discovered during evaluations for cough or coughing up blood. This study reviews coccidioidal cavity cases over 12 years to understand their presentation and management.
Area of Science:
- Mycology
- Infectious Diseases
- Pulmonology
Background:
- Coccidioides species are endemic fungi in the Western Hemisphere.
- Inhalation is the primary route of infection, often leading to symptomatic pneumonia.
- Complications include pulmonary sequelae and extrapulmonary dissemination.
Purpose of the Study:
- To investigate the clinical spectrum of coccidioidal cavities.
- To analyze the diagnostic and management strategies for these cavities.
- To review patient data over a 12-year period at Kern Medical.
Main Methods:
- Retrospective cohort study.
- Analysis of patient records from Kern Medical (last 12 years).
- Review of imaging, clinical presentation, and treatment outcomes for coccidioidal cavities.
Main Results:
- Cavitary lung disease is a significant manifestation of Coccidioides infection.
- Presentation varies, including incidental findings or symptoms like cough and hemoptysis.
- Management strategies are tailored to disease severity and extent.
Conclusions:
- Coccidioidal cavities represent a spectrum of disease requiring careful evaluation.
- Effective management involves a multidisciplinary approach.
- Understanding the presentation aids in timely diagnosis and treatment.
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