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Updated: Jul 29, 2025

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
A hole lot of trouble: Severe bilateral anastomotic dehiscence following bilateral single sequential lung transplant
Cameron White1,2,3, Alice Stuart1, Marshall Plit1
1Department of Medicine The Alfred, 55 Commercial Road Melbourne Victoria Australia.
Abstract:
Airway complications post lung transplant including ischaemia and dehiscence have a significant associated mortality (2%-4%) and morbidity. We describe a case of a 22-year-old female who developed significant bilateral anastomotic dehiscence with severe ischaemia following a bilateral single sequential lung transplant (BSSLTx). Following an intensive antimicrobial regimen, judicious bronchoscopic surveillance, and a prolonged inpatient stay, the dehiscence resolved without requiring further surgical intervention. Our case highlights a space in the literature for further research with regard to airway complications post-lung transplant and their management.

