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Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

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Antithrombotic therapy in the management of hospitalised patients with COVID-19

Ioannis Koulas1, Mark Goldin1,2, Sam Schulman3

  • 1Institute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.

British Journal of Hospital Medicine (London, England : 2005)
|May 26, 2023
PubMed

Insights

Hospitalized patients with COVID-19 face high risks of blood clots. This review summarizes guidelines on thromboprophylaxis to prevent these events in hospitalized and recently discharged COVID-19 patients.

Area of Science:

  • Internal Medicine
  • Hematology
  • Infectious Diseases

Background:

  • Hospitalized patients with COVID-19 have an elevated risk of thromboembolic events during hospitalization and post-discharge.
  • Observational studies prompted numerous randomized controlled trials to determine effective thromboprophylaxis strategies.

Purpose of the Study:

  • To review and summarize evidence-based guideline recommendations for managing antithrombotic therapy in COVID-19 patients.
  • To provide a practical tool for hospital physicians managing COVID-19 patients' thromboprophylaxis.

Main Methods:

  • Review of evidence-based guidelines from the International Society on Thrombosis and Haemostasis.
  • Inclusion of a good clinical practice statement addressing areas with limited high-quality evidence.

Main Results:

  • Guidelines provide recommendations for antithrombotic therapy during hospitalization and post-discharge for COVID-19 patients.
  • A supplementary statement addresses practical considerations for managing thromboprophylaxis.

Conclusions:

  • The summarized guidelines offer essential information for clinicians.
  • This review serves as a quick reference for optimal thromboprophylaxis in COVID-19 patients.

Keywords:
AnticoagulantsAntiplateletsArterial thromboembolismCoronavirus disease 2019HospitalisationISTH guidelinesVenous thromboembolism

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