Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biofilms

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Development and validation of a clinical prediction model for acupuncture response in community-dwelling patients with chronic low back pain: a retrospective cohort study.

BMC health services research·2026

Same author

Continuous N supply at a low temperature produces less N<sub>2</sub>O emission in a semi-arid grassland soil.

Frontiers in microbiology·2026

Same author

Ecological Roles of Biodegradable Mulch Film on Soil Nutrients and Microbes.

Biology·2026

Same author

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work-Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Active ROP2 triggers leaf senescence and orchestrates the growth-senescence trade-off under nitrogen starvation.

Plant signaling & behavior·2026

Same author

Correction: Bio-organic fertilizers modulate the rhizosphere bacterial community to improve plant yield in reclaimed soil.

Frontiers in plant science·2026

Same journal

Cellulose-based MnO<sub>2</sub> nanocomposites for the efficient adsorption of copper (II) ions from aqueous solutions.

International journal of biological macromolecules·2026

Same journal

Efficient isolation of cellulose from Arundo donax L. using deep eutectic solvent for the preparation of regenerated fiber.

International journal of biological macromolecules·2026

Same journal

Proteomic characterization of cellular responses to the fish allergen β-parvalbumin using ZenoSWATH-MS.

International journal of biological macromolecules·2026

Same journal

Lignin-based macromolecular composite solid electrolyte enabling high-performance sodium metal batteries via MgF<sub>2</sub>-assisted ion dissociation.

International journal of biological macromolecules·2026

Same journal

In situ self-growth nano-selenium-loaded peptidoglycan-based biomimetic bioparticles as a versatile immunoregulatory delivery platform for subunit vaccines.

International journal of biological macromolecules·2026

Same journal

Targeted depolymerization of waste cotton textiles mediated by deep eutectic solvents: High-value recycling of waste cotton textiles into regenerated fibers.

International journal of biological macromolecules·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 29, 2025

Generation of Alginate Microspheres for Biomedical Applications

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

Alginate: Microbial production, functionalization, and biomedical applications.

Jianfei Wang¹, Shijie Liu¹, Jiaqi Huang²

¹Department of Chemical Engineering, SUNY College of Environmental Science and Forestry, Syracuse, NY 13210, United States.

International Journal of Biological Macromolecules

|May 26, 2023

Summary

This summary is machine-generated.

Microbial alginates offer customizable, stable properties for biomedical uses. Utilizing industrial wastes and advanced techniques can reduce costs and enhance alginate applications in areas like drug delivery and tissue engineering.

Keywords:

Alginate Alginate-based composite Biomedical application Cheap carbon sources Chemical functionalization Microbial production

More Related Videos

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

Fabrication and Use of Dry Macroporous Alginate Scaffolds for Viral Transduction of T Cells

Fabrication and Use of Dry Macroporous Alginate Scaffolds for Viral Transduction of T Cells

Published on: September 9, 2022

Related Experiment Videos

Last Updated: Jul 29, 2025

Generation of Alginate Microspheres for Biomedical Applications

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

Fabrication and Use of Dry Macroporous Alginate Scaffolds for Viral Transduction of T Cells

Fabrication and Use of Dry Macroporous Alginate Scaffolds for Viral Transduction of T Cells

Published on: September 9, 2022

Area of Science:

Biomaterials Science
Biotechnology
Chemical Engineering

Background:

Alginates, natural polysaccharides, are valuable in food, pharma, and environmental sectors due to their gelling, biocompatible, and biodegradable properties.
Algae-derived alginates face limitations in molecular consistency for advanced biomedical applications.
Microbial alginate production presents an attractive alternative for tailored alginate molecules with stable characteristics.

Approach:

Investigating the use of carbon-rich industrial wastes (sugar, dairy, biodiesel) as cost-effective substrates for microbial alginate production.
Exploring fermentation parameter control and genetic engineering to enhance microbial alginate yield and customize molecular composition.
Reviewing alginate functionalization techniques (e.g., functional group modification, crosslinking) to improve mechanical and biochemical properties for specific biomedical needs.

Key Points:

Microbial alginate production offers enhanced control over molecular weight and composition compared to algae-based sources.
Utilizing industrial byproducts as feedstocks significantly reduces the production costs of microbial alginates.
Alginate functionalization and the development of alginate-based composites are crucial for advanced biomedical applications.

Conclusions:

Sustainable production of high-value microbial alginates is achievable through optimized fermentation and feedstock selection.
Functionalized alginates and composite materials show great promise for applications in wound healing, drug delivery, and tissue engineering.
Further research into microbial alginate production and modification will unlock their full potential in the biomedical field.