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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
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Related Experiment Video

Updated: Jul 29, 2025

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
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ACR Appropriateness Criteria® Monitoring Response to Neoadjuvant Systemic Therapy for Breast Cancer: 2022 Update.

, Jessica H Hayward1, Olivia E Linden2

  • 1University of California, San Francisco, San Francisco, California.

Journal of the American College of Radiology : JACR
|May 26, 2023
PubMed
Summary

This guideline details imaging for breast cancer during neoadjuvant chemotherapy. It ensures accurate response assessment for treatment decisions, utilizing evidence-based criteria.

Keywords:
AUCAppropriate Use CriteriaAppropriateness CriteriaMRIbreast cancerdigital mammographyneoadjuvant chemotherapyultrasound

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Area of Science:

  • Radiology
  • Oncology

Background:

  • Accurate imaging is crucial for assessing breast cancer response to neoadjuvant chemotherapy.
  • Treatment decisions are heavily influenced by the evaluation of therapeutic efficacy.

Framework:

  • Presents evidence-based guidelines for breast cancer imaging before, during, and after neoadjuvant chemotherapy.
  • Developed by the American College of Radiology Appropriateness Criteria, reviewed by a multidisciplinary panel.
  • Utilizes systematic literature analysis and established methodologies like GRADE for evidence evaluation.

Implementation:

  • Employs the RAND/UCLA Appropriateness Method to determine the suitability of imaging and treatment procedures.
  • Guidelines are reviewed annually to incorporate the latest medical evidence.
  • Expert opinion serves as a primary source when peer-reviewed literature is limited or inconclusive.

Implications:

  • Facilitates standardized and evidence-based imaging practices in neoadjuvant chemotherapy for breast cancer.
  • Aims to optimize patient management and treatment strategies through accurate response assessment.
  • Enhances clinical decision-making by providing a robust framework for interpreting imaging findings.