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Updated: Jul 29, 2025

Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Leadless cardiac pacing: Results from a large single-centre experience
Thibault Lenormand1, Kassem Abou Khalil1, Alexandre Bodin1
1Department of Cardiology, Tours University Hospital, 37000 Tours, France.
Leadless cardiac pacing offers a safe and effective alternative to traditional transvenous pacemakers. This study confirms its efficacy in a high-volume center, showing excellent outcomes for both first and second-generation devices.
Area of Science:
- Cardiology
- Medical Devices
- Electrophysiology
Background:
- Leadless cardiac pacing is an emerging alternative to transvenous pacing.
- Assessing real-world outcomes of leadless pacemakers is crucial.
Approach:
- Retrospective observational study of 400 consecutive leadless pacemaker implantations.
- Comparison of first-generation (Micra™ VR) and second-generation (Micra™ AV) devices.
- Evaluation of complications and electrical parameters during follow-up.
Key Points:
- High implantation success rate (99.5%) with a low perioperative complication rate (3.5%).
- Stable pacing thresholds observed in 96.5% of patients.
- Early discharge (87.5%) achieved, indicating good patient recovery.
Conclusions:
- Leadless cardiac pacing demonstrates safety and efficiency in a high-volume center.
- Outcomes were comparable between Micra™ VR and Micra™ AV devices.
- Supports leadless pacing as a viable alternative to conventional pacing.
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