Related Experiment Video
Updated: Jul 29, 2025
Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Leadless cardiac pacing: Results from a large single-centre experience
Thibault Lenormand1, Kassem Abou Khalil1, Alexandre Bodin1
1Department of Cardiology, Tours University Hospital, 37000 Tours, France.
Insights
Leadless cardiac pacing offers a safe and effective alternative to traditional transvenous pacemakers. This study confirms its efficacy in a high-volume center, showing excellent outcomes for both first and second-generation devices.
Area of Science:
- Cardiology
- Medical Devices
- Electrophysiology
Background:
- Leadless cardiac pacing is an emerging alternative to transvenous pacing.
- Assessing real-world outcomes of leadless pacemakers is crucial.
Approach:
- Retrospective observational study of 400 consecutive leadless pacemaker implantations.
- Comparison of first-generation (Micra™ VR) and second-generation (Micra™ AV) devices.
- Evaluation of complications and electrical parameters during follow-up.
Key Points:
- High implantation success rate (99.5%) with a low perioperative complication rate (3.5%).
- Stable pacing thresholds observed in 96.5% of patients.
- Early discharge (87.5%) achieved, indicating good patient recovery.
Conclusions:
- Leadless cardiac pacing demonstrates safety and efficiency in a high-volume center.
- Outcomes were comparable between Micra™ VR and Micra™ AV devices.
- Supports leadless pacing as a viable alternative to conventional pacing.
Background:
The efficacy and safety of leadless cardiac pacing as an alternative to conventional transvenous cardiac pacing in selected patients have been widely reported.
Aim:
To report the experience of a high-volume implantation centre with older and new generations of leadless pacemakers.
Methods:
This retrospective observational study included the first consecutive 400 patients who underwent implantation of a leadless pacemaker in our centre. Complications and electrical parameters were evaluated during follow-up, comparing patients implanted with first-generation (Micra™ VR) and second-generation (Micra™ AV) leadless pacemakers (Medtronic, Minneapolis, MN, USA). Data were collected by a review of medical files.
Results:
Among 400 procedures, there were 328 Micra™ VR pacemakers and 72 Micra™ AV pacemakers implanted, followed for a median of 16 months (694 patient-years). The mean age was 77 years and both groups had a high burden of co-morbidities. Implantation success rate was 99.5%. A total of 87.5% of patients were discharged the day after the procedure. The pacing threshold remained stable and<2V in 96.5% of all patients. The perioperative complication rate at 30 days was 3.5%. Outcomes were similar between the two groups.
Conclusion:
Leadless cardiac pacing is a safe and efficient alternative to conventional transvenous cardiac pacing.
More Related Videos
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
10:17Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
