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Functional Characterization of the Putative POT from Clostridium perfringens

Hani Gharabli1, Maria Rafiq1, Anna Iqbal1

  • 1Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

Biology
|May 27, 2023
PubMed
Summary

This study reveals atypical transport mechanisms in Clostridium perfringens proton-coupled oligopeptide transporters (CPEPOT). Unlike other bacterial POTs, CPEPOT exhibits substrate exchange, not proton symport, for peptide uptake.

Keywords:
Clostridium perfringensPOTsmajor facilitator superfamilypeptide transport

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