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Updated: Jul 29, 2025

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
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Exploiting Patch Sizes and Resolutions for Multi-Scale Deep Learning in Mammogram Image Classification.

Gonzalo Iñaki Quintana1,2, Zhijin Li1, Laurence Vancamberg1

  • 1GE HealthCare, 283 Rue de la Minière, 78530 Buc, France.

Bioengineering (Basel, Switzerland)
|May 27, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces multi-scale deep learning classifiers for breast cancer detection using 2D mammograms. Combining various patch sizes and resolutions improves diagnostic accuracy, enhancing computer-aided detection (CAD) systems.

Keywords:
artificial intelligencebreast imagingcomputer aided detection or diagnosis (CAD)convolutional neural networks (CNNs)deep learningmulti-scale classification

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Oncology

Background:

  • Deep learning (DL) shows promise for breast cancer screening via computer-aided detection (CAD) systems.
  • Patch-based DL methods for 2D mammogram classification face limitations due to fixed patch sizes and unclear resolution impacts.
  • Optimal patch size and image resolution for detecting diverse breast cancer lesion sizes remain challenging.

Purpose of the Study:

  • To investigate the influence of patch size and image resolution on DL classifier performance for 2D mammograms.
  • To develop and evaluate novel multi-scale classifier architectures that integrate diverse patch sizes and resolutions.
  • To enhance the accuracy of DL-based CAD systems for breast cancer screening.

Main Methods:

  • Proposed multi patch-size and multi-resolution DL classifier architectures.
  • Implemented multi-scale classification by combining varied patch sizes and input image resolutions.
  • Evaluated classifier performance on the public CBIS-DDSM dataset and an internal dataset.

Main Results:

  • The multi-scale classifier achieved an Area Under the Curve (AUC) of 0.809 on the CBIS-DDSM dataset, a 3% improvement.
  • On an internal dataset, the multi-scale classifier reached an AUC of 0.722, a 5% improvement.
  • The proposed multi-scale approach outperformed baseline single patch size and single resolution classifiers.

Conclusions:

  • Multi-scale classification effectively addresses the limitations of fixed patch sizes and single resolutions in mammogram analysis.
  • Integrating multiple patch sizes and resolutions significantly enhances the performance of DL-based CAD systems for breast cancer screening.
  • The developed multi-scale architectures offer a promising advancement for more accurate and reliable mammogram interpretation.