Related Experiment Video
Updated: Jul 29, 2025
06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.3K
Sebaceous Neoplasms
Ilias Papadimitriou1, Efstratios Vakirlis1, Elena Sotiriou1
1First Department of Dermatology and Venereology, School of Health Science, Aristotle University of Thessaloniki, 54643 Thessaloniki, Greece.
Diagnostics (Basel, Switzerland)
|May 27, 2023
Summary
Sebaceous neoplasms, often benign skin tumors on the face and neck, can be linked to Muir-Torre Syndrome. Early detection and diagnosis through histopathology are crucial for managing these sebaceous gland tumors.
Area of Science:
- Dermatology
- Oncology
Background:
- Sebaceous neoplasms are tumors originating from sebaceous glands, predominantly affecting the face and neck.
- While most sebaceous neoplasms are benign, malignant variants and their association with Muir-Torre Syndrome warrant attention.
Purpose of the Study:
- To review clinical and dermoscopic features of sebaceous neoplasms.
- To outline management strategies for sebaceous carcinoma, sebaceoma/sebaceous adenoma, and sebaceous hyperplasia.
- To highlight the significance of Muir-Torre Syndrome in patients with multiple sebaceous tumors.
Main Methods:
- Literature analysis of clinical and dermoscopic features.
- Review of management procedures for various sebaceous neoplasms.
- Emphasis on diagnostic approaches for Muir-Torre Syndrome.
Main Results:
- Sebaceous neoplasms exhibit distinct clinical and dermoscopic characteristics.
- Malignant sebaceous neoplasms are uncommon but associated with Muir-Torre Syndrome.
- Diagnostic workup for suspected Muir-Torre Syndrome includes excision, histopathology, immunohistochemistry, and genetics.
Conclusions:
- Accurate diagnosis of sebaceous neoplasms is essential.
- Muir-Torre Syndrome should be considered in patients with multiple sebaceous tumors.
- Comprehensive evaluation aids in appropriate patient management and treatment.
Keywords:
Muir–Torre Syndromesebaceomasebaceous adenomasebaceous carcinomasebaceous hyperplasiasebaceous neoplasmsMore Related Videos
Related Concept Videos
01:21Accessory Structures of the Skin: Sebaceous Glands
2.0K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
2.0K
01:30Skin Cancer
4.3K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.3K
01:08Exocrine Glands: Methods of Secretion
4.3K
Exocrine glands are those that release their secretions through ducts. Based on their mode of secretion, they can be classified into merocrine, apocrine, and holocrine.
Merocrine Secretion
Merocrine secretion is the most common type of exocrine secretion. The secretions are enclosed in vesicles and moved to the cell's apical surface, where the contents are released by exocytosis. For example, mucous, a watery secretion rich in the glycoprotein mucin, is a merocrine secretion. The eccrine...
Merocrine Secretion
Merocrine secretion is the most common type of exocrine secretion. The secretions are enclosed in vesicles and moved to the cell's apical surface, where the contents are released by exocytosis. For example, mucous, a watery secretion rich in the glycoprotein mucin, is a merocrine secretion. The eccrine...
4.3K
01:06Multipotency and Niche of Bulge Stem Cell
3.7K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
3.7K
02:23Abnormal Proliferation
4.6K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.6K
01:20Classification of Epithelial Tissues: Glandular Epithelium
9.0K
The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Multicellular glands are formed during early development when epithelial budding...
9.0K