Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Drug Nomenclature01:17

Drug Nomenclature

1.8K
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
1.8K
Routes of Drug Administration: Parenteral01:25

Routes of Drug Administration: Parenteral

2.0K
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
2.0K
Drug Excretion: Pulmonary and Glandular Routes01:22

Drug Excretion: Pulmonary and Glandular Routes

167
Gaseous substances like general anesthetics are absorbed and excreted through the lungs via simple diffusion. This process depends on factors such as pulmonary blood flow, respiration rate, and the substance's solubility. Gaseous anesthetics like nitrous oxide with low blood solubility are excreted rapidly, while compounds like alcohol, with high blood and tissue solubility, are excreted slowly.
Drugs can also be excreted in breast milk, which is crucial for breastfeeding infants. The...
167
Drug Classes and Categories01:25

Drug Classes and Categories

2.1K
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
2.1K
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

3.6K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drug-associated acute pancreatitis in paediatric versus adult reports: a disproportionality analysis using FAERS.

European journal of pediatrics·2026
Same author

Time-dependent pattern of liver injury biomarkers in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia.

European journal of pediatrics·2026
Same author

Blood fatty acid changes in preterm infants in a trial of enteral DHA supplementation.

Pediatric research·2026
Same author

Corrigenda: Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach.

JMIR research protocols·2026
Same author

Emerging evidence on the safety of enteral feeding during PRBC transfusion in preterm infants.

Pediatric research·2026
Same author

Neonatal PBPK model of midazolam and its metabolites for perinatal asphyxia and therapeutic hypothermia.

British journal of clinical pharmacology·2026

Related Experiment Video

Updated: Jul 29, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.1K

Neonatal Drug Formularies-A Global Scope.

Dotan Shaniv1,2, Srinivas Bolisetty3, Thomas E Young4,5,6

  • 1Pharmacy Services, Kaplan Medical Center (Clalit Health Services), Pasternak St., P.O. Box 1, Rehovot 76100, Israel.

Children (Basel, Switzerland)
|May 27, 2023
PubMed
Summary

Neonatal drug information formularies vary significantly in content and structure worldwide. Understanding these differences is crucial for clinicians to ensure safe and effective medication use in neonates.

Keywords:
drug databasedrug formularydrug informationneonatalpediatric

More Related Videos

A Neonatal Rodent Model of Retroorbital Vein Injection
04:39

A Neonatal Rodent Model of Retroorbital Vein Injection

Published on: February 23, 2024

6.2K
A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
04:21

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

Published on: August 4, 2021

6.0K

Related Experiment Videos

Last Updated: Jul 29, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.1K
A Neonatal Rodent Model of Retroorbital Vein Injection
04:39

A Neonatal Rodent Model of Retroorbital Vein Injection

Published on: February 23, 2024

6.2K
A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
04:21

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

Published on: August 4, 2021

6.0K

Area of Science:

  • Neonatal pharmacology and drug information science.

Background:

  • Neonatal drug information (DI) is critical for safe pharmacotherapy in neonates.
  • Drug labels often lack essential neonatal DI, making formularies vital clinical tools.

Purpose of the Study:

  • To identify and compare global neonatal formularies for content, structure, and workflow.
  • To raise awareness of existing neonatal drug information resources.

Main Methods:

  • Systematic identification of neonatal formularies through various channels.
  • Questionnaire-based data collection on formulary function, structure, and content.
  • Original extraction tool used to collect DI for common neonatal drugs.

Main Results:

  • Eight neonatal formularies were identified globally (Europe, USA, Australia-New Zealand, Middle East).
  • Six formularies responded, revealing distinct workflows, monograph templates, styles, and update routines.
  • Variations noted in focus areas of DI, initiative type, and funding.

Conclusions:

  • Neonatal formularies exhibit significant differences in characteristics and content.
  • Clinicians must be aware of these variations to utilize formularies effectively for optimal patient care.