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Published on: November 2, 2020
Non-Thermal Atmospheric Pressure Plasma Application in Endodontics
Ana Bessa Muniz1, Mariana Raquel da Cruz Vegian1, Lady Daiane Pereira Leite1
1Department of Environment Engineering and Sciences Applied to Oral Health Graduate Program, São José dos Campos Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12247-016, SP, Brazil.
Non-thermal atmospheric pressure plasma (NTPP) shows promise for eliminating endodontic microorganisms like Enterococcus faecalis and Candida albicans. Combining NTPP with conventional solutions enhances disinfection, but further research is needed for clinical application.
Area of Science:
- Dental research
- Plasma medicine
- Antimicrobial technologies
Background:
- Endodontic treatment failure is often linked to persistent microorganisms and biofilms.
- Conventional irrigation solutions have limitations in completely eliminating endodontic pathogens.
- Non-thermal atmospheric pressure plasma (NTPP) offers a novel approach for microbial disinfection.
Purpose of the Study:
- To review and evaluate the potential of Non-thermal atmospheric pressure plasma (NTPP) in Endodontics.
- To assess the antimicrobial efficacy of NTPP against key endodontic microorganisms.
- To explore the application methods and influencing parameters of NTPP in endodontic disinfection.
Main Methods:
- A literature review was conducted across Lilacs, Pubmed, and Ebsco databases.
- Seventeen manuscripts published between 2007 and 2022 meeting inclusion criteria were analyzed.
- Studies evaluated direct NTPP exposure and indirect application via plasma-activated liquids (PAL).
Main Results:
- NTPP demonstrated significant disinfection properties against Enterococcus faecalis and Candida albicans.
- Antimicrobial efficacy increased with plasma exposure time, showing optimal results over eight minutes.
- Combining NTPP with conventional antimicrobial solutions yielded superior results compared to individual treatments, often with shorter exposure times.
Conclusions:
- NTPP exhibits considerable antimicrobial potential for endodontic applications, particularly against common pathogens.
- The synergistic effect of NTPP and conventional solutions is promising for clinical practice.
- Further standardization of direct NTPP application parameters and more research on plasma-activated liquids are necessary.
