Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

30
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
30
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

41
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
41
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

51
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
51
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

48
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
48
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

39
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
39
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

38
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
38

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Positively charged, phenolic hydroxyl and anthraquinone structured polystyrene microspheres targeting dual elimination of bacterial pathogens and pathogen-associated molecular patterns for sepsis therapy.

Journal of materials chemistry. B·2026
Same author

Breaking barriers in peritoneal fibrosis: extracellular vesicles as promising diagnostic and therapeutic strategy.

Annals of medicine·2026
Same author

Bibliometric analysis of sacubitril/valsartan in the management of chronic kidney disease (2013-2025).

Renal failure·2026
Same author

The Effect of Heparin-Grafted Chitosan-Cellulose Composite Microspheres on the Removal of Endotoxins and Circulating Histones in a Septic Rabbit Model: An In Vivo Study.

Biomedicines·2026
Same author

Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets.

MedComm·2025
Same author

Genetic and Pharmacological Inhibition of NOX4 Protects Against Rhabdomyolysis-Induced Acute Kidney Injury Through Suppression of Endoplasmic Reticulum Stress.

Antioxidants (Basel, Switzerland)·2025

Related Experiment Video

Updated: Jul 29, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

720

Acute Kidney Failure: Current Challenges and New Perspectives.

Shanshan Chen1, Yupei Li1, Baihai Su1

  • 1Department of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, China.

Journal of Clinical Medicine
|May 27, 2023
PubMed
Summary

Acute kidney injury (AKI) is a sudden decline in kidney function, marked by elevated creatinine and decreased urine output. Early detection and intervention are crucial for managing this critical condition.

More Related Videos

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
07:58

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury

Published on: July 17, 2016

8.9K
Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
08:53

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Published on: August 9, 2014

44.6K

Related Experiment Videos

Last Updated: Jul 29, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

720
Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
07:58

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury

Published on: July 17, 2016

8.9K
Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
08:53

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Published on: August 9, 2014

44.6K

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Biomedical Science

Background:

  • Acute kidney injury (AKI) signifies a rapid deterioration of renal function.
  • Conventional diagnostics for AKI include monitoring serum creatinine levels and urinary output.
  • Understanding the pathophysiology of AKI is essential for timely intervention.

Discussion:

  • The definition of AKI relies on specific clinical markers indicating impaired kidney function.
  • Prompt recognition of AKI is vital for patient outcomes.
  • Further research into AKI mechanisms can improve diagnostic and therapeutic strategies.

Key Insights:

  • AKI is characterized by abrupt loss of kidney function.
  • Serum creatinine and urinary output are key indicators for diagnosing AKI.
  • The clinical definition emphasizes the sudden onset of renal impairment.

Outlook:

  • Advancements in AKI research aim to refine diagnostic criteria and treatment protocols.
  • Future studies may explore novel biomarkers for earlier AKI detection.
  • Improving patient outcomes in AKI necessitates a multi-faceted approach involving early diagnosis and effective management.