Post-Operative Complications after Foramen Magnum Decompression with Duraplasty Using Different Graft Materials in...

Despite extensive investigations, the choice of graft material for reconstructive duraplasty after foramen magnum decompression for Chiari type I malformation (CMI) is still a topic of discussion. The authors performed a systematic review and meta-analysis of the literature examining the post-operative complications in adult patients with CMI after foramen magnum decompression and duraplasty (FMDD) using different graft materials. Our systematic review included 23 studies with a total of 1563 patients with CMI who underwent FMDD with different dural substitutes. The most common complications were pseudomeningocele (2.7%, 95% CI 1.5-3.9%, p < 0.01, I² = 69%) and CSF leak (2%, 95% CI 1-2.9%, p < 0,01, I² = 43%). The revision surgery rate was 3% (95% CI 1.8-4.2%, p < 0.01, I² = 54%). A lower rate of pseudomeningocele was observed with autologous duraplasty when compared with synthetic duraplasty (0.7% [95% CI 0-1.3%] vs. 5.3% [95% CI 2.1-8.4%] p < 0.01). The rate of CSF leak and revision surgery was lower after autologous duraplasty than after non-autologous dural graft (1.8% [95% CI 0.5-3.1%] vs. 5.3% [95% CI 1.6-9%], p < 0.01 and 0.8% [95% CI 0.1-1.6%] vs. 4.9% [95% CI 2.6-7.2%] p < 0.01, respectively). Autologous duraplasty is associated with a lower rate of post-operative pseudomeningocele and reoperation. This information should be considered when planning duraplasty after foramen magnum decompression in patients with CMI.