Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Noninvasive physical plasma in vulvar lichen sclerosus: a prospective pilot study.

International journal of women's dermatology·2026
Same author

Vaginal cuff dehiscence and bowel evisceration as a late-onset complication of vaginal vault prolapse: a case report.

Journal of medical case reports·2026
Same author

Procurement in German office based ambulatory physician practices: system specific challenges and evidence based management strategies.

Health economics review·2026
Same author

Feasibility and safety of 4DryField<sup>®</sup> PH as a hemostatic agent in ovarian surgery on fertility: a pilot randomized study.

Archives of gynecology and obstetrics·2026
Same author

Clinical outcomes and practical management implications in rudimentary horn pregnancies: a systematic review and pooled analysis (2010-2025).

Archives of gynecology and obstetrics·2026
Same author

Fertility Preservation for Patients with Malignant Disease. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/082, May 2025).

Geburtshilfe und Frauenheilkunde·2026

Related Experiment Video

Updated: Jul 29, 2025

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
07:37

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae

Published on: April 30, 2018

14.3K

Immune Cell Functionality during Decidualization and Potential Clinical Application.

Matthias B Stope1, Alexander Mustea1, Nicole Sänger2

  • 1Department of Gynecology and Gynecological Oncology, University Hospital Bonn, 53127 Bonn, Germany.

Life (Basel, Switzerland)
|May 27, 2023
PubMed
Summary

Decidual leukocytes are crucial for pregnancy, but their roles in idiopathic infertility require further study. Understanding these immune cells can advance reproductive immunology and fertility treatments.

Keywords:
NK cellsdeciduaearly pregnancy developmentfetal toleranceimplantationinnate lymphoid cellsmacrophagesplacentationreproductive immunology

More Related Videos

Isolation of Human Endometrial Stromal Cells for In Vitro Decidualization
14:55

Isolation of Human Endometrial Stromal Cells for In Vitro Decidualization

Published on: September 1, 2018

10.3K
Isolation of Mouse Endometrial Epithelial and Stromal Cells for In Vitro Decidualization
08:37

Isolation of Mouse Endometrial Epithelial and Stromal Cells for In Vitro Decidualization

Published on: March 2, 2017

24.3K

Related Experiment Videos

Last Updated: Jul 29, 2025

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
07:37

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae

Published on: April 30, 2018

14.3K
Isolation of Human Endometrial Stromal Cells for In Vitro Decidualization
14:55

Isolation of Human Endometrial Stromal Cells for In Vitro Decidualization

Published on: September 1, 2018

10.3K
Isolation of Mouse Endometrial Epithelial and Stromal Cells for In Vitro Decidualization
08:37

Isolation of Mouse Endometrial Epithelial and Stromal Cells for In Vitro Decidualization

Published on: March 2, 2017

24.3K

Area of Science:

  • Reproductive Immunology
  • Cellular Biology
  • Obstetrics & Gynecology

Background:

  • Leukocytes constitute a significant portion of the decidua during implantation.
  • The precise roles of decidual immune cells in pregnancy success and failure are not fully elucidated.
  • Decidual immune dysregulation is a suspected factor in idiopathic infertility.

Purpose of the Study:

  • To review the functions of immune cells within the decidua.
  • To discuss current clinical diagnostics and interventions related to decidual immune factors.
  • To highlight the need for further research into reproductive immunology mechanisms.

Main Methods:

  • Literature review of immune cell functions in the decidua.
  • Analysis of available diagnostic tools for immune-related factors.
  • Discussion of current and potential therapeutic interventions.

Main Results:

  • A growing number of diagnostic tools for immune factors are commercially available.
  • Intervention options for immune-related infertility remain limited and understudied.
  • Understanding immune cell mechanisms is critical for advancing reproductive immunology.

Conclusions:

  • Decidual immune cells play a vital role in pregnancy, yet their mechanisms are not fully understood.
  • While diagnostics are advancing, therapeutic interventions for immune-related infertility require significant development.
  • Translational research is essential to bridge the gap between reproductive immunology findings and clinical applications.