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Updated: Jul 29, 2025

Aerosol-assisted Chemical Vapor Deposition of Metal Oxide Structures: Zinc Oxide Rods
Published on: September 14, 2017
First Results on Zinc Oxide Thick Film Deposition by Inverted Magnetron Sputtering for Cyclotron Solid Targets
Alisa Kotliarenko1,2, Oscar Azzolini1, Sara Cisternino1,3
1Legnaro National Laboratories, Italian National Institute for Nuclear Physics (LNL-INFN), 35020 Legnaro, Italy.
This study introduces an inverted magnetron sputtering prototype for efficient medical radionuclide production. The new method conserves expensive materials, crucial for radiopharmaceutical manufacturing.
Area of Science:
- Nuclear Medicine
- Materials Science
- Accelerator Physics
Background:
- Magnetron sputtering is a key technology for producing medical radionuclides using low-energy cyclotrons.
- High material costs and potential losses limit the use of isotopically enriched metals in current methods.
- Efficient material utilization and recovery are vital for meeting the increasing demand for theranostic radionuclides.
Purpose of the Study:
- To develop an alternative magnetron sputtering configuration to overcome material loss drawbacks.
- To create a novel inverted magnetron prototype for depositing thick films (tens of μm) for solid target manufacturing.
- To evaluate the feasibility and performance of this new approach for radiopharmaceutical applications.
Main Methods:
- Development of a novel inverted magnetron sputtering prototype.
- Deposition of Zinc Oxide (ZnO) films (20-30 μm) onto Niobium (Nb) substrates.
- Characterization using Scanning Electron Microscopy (SEM) and X-ray Diffractometry (XRD).
- Assessment of thermomechanical stability under a medical cyclotron's proton beam.
Main Results:
- Successful deposition of ZnO films with thicknesses of 20-30 μm.
- Characterization confirmed film properties via SEM and XRD.
- Demonstrated thermomechanical stability of the deposited films under simulated cyclotron conditions.
- The inverted magnetron configuration was utilized for solid target manufacturing for the first time.
Conclusions:
- The developed inverted magnetron prototype offers a material-saving approach for solid target manufacturing.
- This technology is promising for the cost-effective production of medical radionuclides.
- Further improvements and utilization in the radiopharmaceutical field are anticipated.
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