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Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK)

Nina Nauwelaerts1, Julia Macente1, Neel Deferm1,2

  • 1Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.

Pharmaceutics
|May 27, 2023
PubMed

Keywords:
breastfeedingdaily infant dosagehuman milkin silicolactationmedicinesmilk-to-plasma ratio (M/P ratio)pharmacokineticsphysiologically-based pharmacokinetic (PBPK) modelling and simulationrelative infant dose

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