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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Acne Fulminans: A Narrative Review.

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Acne fulminans, a severe inflammatory acne, predominantly affects adolescent males, often triggered by isotretinoin. Systemic corticosteroids are the primary treatment, though quality of life impacts are underreported.

Keywords:
AcneAcne fulminansAcnéAcné fulminansCalidad de vidaQuality of life

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Area of Science:

  • Dermatology
  • Inflammatory Diseases
  • Medical Literature Review

Background:

  • Acne fulminans is a rare, severe inflammatory acne with significant scarring potential.
  • Lesion severity and scarring negatively impact patient quality of life.
  • Understanding clinical and demographic characteristics is crucial for management.

Approach:

  • Conducted a narrative literature review of English and Spanish articles from Medline.
  • Included case reports and case series to analyze 212 cases of acne fulminans.
  • Focused on clinical/demographic features and quality of life impact.

Key Points:

  • Predominantly affects males (91.94%) with a mean age of 16.6 years.
  • Commonly linked to acne vulgaris history (97.63%) and pharmacologic triggers (44.79%), especially isotretinoin (65.28%).
  • Frequently involves the face (89.31%) and trunk (77.86%), with systemic symptoms present in 59.12%.

Conclusions:

  • Acne fulminans primarily impacts adolescent males, often with a history of acne vulgaris.
  • Systemic corticosteroids are the most common treatment, particularly for the subtype with systemic symptoms.
  • The effect of acne fulminans on quality of life remains significantly underreported in the literature.