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Metabolomics and its applications in assisted reproductive technology
1Wuxi No.2 People's Hospital, Jiangnan University Medical Center, Wuxi, Jiangsu, China.
IET Nanobiotechnology
|May 30, 2023
Summary
Metabolomics, a systems biology tool, analyzes metabolites to assess health. This review explores its use in assisted reproductive technology (ART) to evaluate gamete and embryo quality.
Area of Science:
- Systems biology
- Metabolomics
- Omics technology
Background:
- Metabolomics quantifies dynamic metabolite changes for understanding pathophysiology.
- Mass spectrometry (MS) and nuclear magnetic resonance (NMR) are key analytical methods.
- Assisted reproductive technology (ART) involves sperm, oocyte, and embryo manipulation for conception.
Purpose of the Study:
- To review the progress of metabolomics research.
- To explore the application of metabolomics in ART.
- To provide insights for future research and development in ART.
Main Methods:
- Review of existing scientific literature on metabolomics and ART.
- Analysis of studies utilizing metabolomics for ART sample assessment.
- Identification of metabolites for evaluating gamete and embryo quality.
Main Results:
- Metabolomics can measure metabolites in ART samples.
- Metabolites identified through metabolomics can assess gamete and embryo quality.
- Growing evidence supports metabolomics' role in ART.
Conclusions:
- Metabolomics is a valuable tool in ART.
- Further research can optimize metabolomics applications in ART.
- This technology aids in improving ART outcomes.
