Related Experiment Video
Updated: Jul 28, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
Published on: September 9, 2022
[Treatment alternatives for amyopathic MDA5-positive dermatomyositis]
Falk Schumacher1,2, Maximilian Wollsching-Strobel3,4, Doreen Kroppen3,4
1Klinik für Rheumatologie, Krankenhaus Porz am Rhein gGmbH, Urbacher Weg 19, 51149, Köln, Deutschland. f.schumacher@khporz.de.
Abstract:
We report a case of an atypical course of therapy in amyopathic MDA5-antibody-positive dermatomyositis with interstitial lung disease. Due to the poor prognosis, early therapy with cyclophosphamide followed by rituximab was carried out initially in addition to the administration of prednisolone. Due to therapy failure, treatment was switched to mycophenolate mofetil. This showed a surprisingly rapid positive course in terms of interstitial lung disease, skin manifestation, and general disease activity.
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