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Pharmacological Treatment of Neonatal and Juvenile Mice to Study Spermatogenesis
Oleksandr Kirsanov1, Christopher B Geyer2,3
1Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
Methods in Molecular Biology (Clifton, N.J.)
|May 30, 2023
Abstract:
The delivery, to newborn and juvenile mice, of drugs and other compounds that manipulate the physiology or cellular/molecular state -e.g., by activating or inhibiting signaling pathways) is a powerful, yet underutilized approach to studying spermatogenesis. Here, we provide detailed protocols we have optimized in our laboratory for safely and effectively feeding and injecting mice and discuss troubleshooting approaches.

