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Updated: Jul 28, 2025
Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
Published on: February 12, 2011
Quantitative evaluation of acute myocardial infarction by feature-tracking cardiac magnetic resonance imaging
Jun Ye1, Wenxia Zong2, Xing Wu3
1Jun Ye, Department of Radiology, Wuhan No.7 Hospital, Wuhan 430071, Hubei Province, P.R. China.
Insights
Feature-tracking cardiac magnetic resonance (FT-CMR) effectively quantifies acute myocardial infarction (AMI) strain. This non-invasive method aids in predicting ST-elevation myocardial infarction (STEMI) and preventing cardiac remodeling.
Area of Science:
- Cardiology
- Medical Imaging
- Biomedical Engineering
Background:
- Acute myocardial infarction (AMI) poses a significant threat to cardiovascular health.
- Accurate quantitative evaluation of AMI is crucial for timely intervention and management.
- Feature-tracking cardiac magnetic resonance (FT-CMR) offers a potential non-invasive method for assessing myocardial function.
Purpose of the Study:
- To evaluate the diagnostic value of FT-CMR in quantifying acute myocardial infarction (AMI).
- To compare myocardial strain parameters between ST-elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) patients.
- To assess the correlation between FT-CMR parameters and infarct size, and its predictive value for STEMI.
Main Methods:
- Retrospective analysis of FT-CMR examinations in 100 AMI patients (52 STEMI, 48 NSTEMI).
- Comparison of myocardial strain parameters (radial, circumferential, longitudinal) between STEMI and NSTEMI groups.
- Pearson's correlation and Receiver Operating Characteristic (ROC) curve analysis to assess diagnostic value.
Main Results:
- STEMI patients exhibited significantly higher late gadolinium enhancement (LGE)-positive segments compared to NSTEMI patients.
- Myocardial radial, circumferential, and longitudinal strains were significantly reduced in the STEMI group (p<0.05).
- Reduced myocardial strains correlated negatively with LGE-positive segments, and ROC analysis confirmed their diagnostic value for STEMI (p<0.05).
Conclusions:
- FT-CMR is a valuable non-invasive tool for quantitative evaluation of AMI.
- Myocardial strain parameters derived from FT-CMR can effectively differentiate STEMI from NSTEMI.
- FT-CMR aids in predicting STEMI and may guide interventions to prevent adverse ventricular remodeling post-infarction.
Objective:
To assess the value of feature-tracking cardiac magnetic resonance (FT-CMR) imaging in the quantitative evaluation of acute myocardial infarction (AMI).
Methods:
We retrospectively analyzed medical records of patients with acute myocardial infarction (AMI) diagnosed in the Department of Cardiology of Hubei No.3 People's Hospital of Jianghan University from April 2020 to April 2022, who underwent feature-tracking cardiac magnetic resonance (FT-CMR) examination. Based on the electrocardiogram (ECG) findings, patients were divided into ST-elevation myocardial infarction (STEMI) (n=52) and non-STEMI (NSTEMI) (n=48) groups. We compared myocardial strain parameters between the two groups and applied the Pearson's test to reveal any correlations between the left ventricular myocardial strain parameters and the number of late gadolinium enhancement (LGE) positive segments; we assessed the clinical value of FT-CMR for predicting STEMI using a receiver operating characteristic (ROC) curve.
Results:
The number of LGE-positive segments in the STEMI group was significantly higher than that in the NSTEMI group. The myocardial radial, circumferential and longitudinal strains in the STEMI group were significantly lower than those in the NSTEMI group (p<0.05). The number of LGE-positive segments in patients with AMI negatively correlated with the radial, circumferential and longitudinal strains. The results of the ROC curve analysis showed that radial, circumferential and longitudinal strain values have a diagnostic value for STEMI (p<0.05).
Conclusion:
FT-CMR, a non-invasive and rapid method for analyzing myocardial strains, has a high diagnostic value for AMI and should be helpful for the prevention and intervention of ventricular remodeling after myocardial infarctions.
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