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Related Experiment Video

Updated: Jul 28, 2025

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

A vascular syphilitic iris lesion.

Judy L Chen^1,2, Ruth Tessema¹, Parisa Emami-Naeini¹

¹Department of Ophthalmology & Vision Sciences, University of California, Davis, Sacramento, CA, USA.

American Journal of Ophthalmology Case Reports

|May 30, 2023

Summary

This summary is machine-generated.

This study details iris papulosa, a rare sign of ocular syphilis, observed in a 60-year-old man. Imaging revealed distinctive features, aiding diagnosis of this vascular iris mass.

Keywords:

Anterior segment optical coherence tomography Granulomatous uveitis Iris lesion Syphilis Ultrasound biomicroscopy

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Area of Science:

Ophthalmology
Infectious Diseases
Medical Imaging

Background:

Ocular syphilis can present with diverse manifestations, including uveitis.
Iris papulosa is a rare finding in ocular syphilis, necessitating accurate diagnostic imaging.

Observation:

A 60-year-old male presented with granulomatous anterior uveitis and a vascularized iris papule.
Anterior segment optical coherence tomography (AS-OCT) showed a hyperreflective iris lesion with vascular lumens.
Ultrasound biomicroscopy (UBM) identified an echodense mass with hyperechogenicity.

Findings:

AS-OCT and UBM provided characteristic imaging signatures for iris papulosa.
Systemic work-up confirmed syphilis as the underlying cause.
The patient was treated with topical steroids and parenteral penicillin.

Implications:

Iris papulosa, visualized via AS-OCT and UBM, is a potential indicator of ocular syphilis.
This case highlights the importance of considering syphilis in the differential diagnosis of undifferentiated vascular iris masses.
Advanced imaging techniques are crucial for characterizing rare ocular manifestations of syphilis.