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A case report of Vibrio vulnificus sepsis in a diabetic patient

Li Jin1, Wenjie Liao2, Mengxiao Jiang1

  • 1Department of Emergency, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, 226001, Jiangsu, China.

Heliyon
|May 30, 2023
PubMed

Insights

A rare Vibrio vulnificus infection in an elderly diabetic patient, caused by a sea shrimp injury, highlights the importance of rapid diagnosis using next-generation sequencing (NGS). Prompt treatment significantly improved the patient's outcome.

Area of Science:

  • Microbiology
  • Infectious Diseases

Background:

  • Vibrio vulnificus is a Gram-negative bacterium causing severe infections, particularly in immunocompromised individuals.
  • Diabetic patients with alcoholism are at higher risk for severe Vibrio vulnificus infections.

Observation:

  • An 85-year-old male with diabetes and alcoholism developed a severe Vibrio vulnificus infection after a sea shrimp stab wound.
  • Rapid deterioration was observed due to bacterial virulence and patient comorbidities.

Findings:

  • Next-generation sequencing (NGS) and blood culture enabled rapid diagnosis of Vibrio vulnificus.
  • Effective antibiotic selection via drug sensitivity testing was crucial.
  • Timely antimicrobial therapy, debridement, and drainage led to improved prognosis.

Implications:

  • This case underscores the utility of NGS in diagnosing Vibrio vulnificus infections quickly.
  • Highlights the critical need for prompt, targeted treatment in high-risk patients.
  • Provides a clinical reference for managing Vibrio vulnificus in diabetic individuals exposed to marine environments or seafood.
Keywords:
Diabetic patientsHydrogen peroxideSepsisVibrio vulnificusVibrio vulnificus infection

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