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Potential effects of bisphenol A on diabetes mellitus and its chronic complications: A narrative review
Wei Jiang1, Kaixi Ding1, Wenjie Huang2
1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.
Abstract:
Diabetes mellitus (DM) is a metabolic disease caused by multiple factors such as genetics, environment, and lifestyle. Bisphenol A (BPA), as one of the most common endocrine-disrupting chemicals (EDCs), has been strongly implicated in the development of type 2 diabetes mellitus (T2DM). BPA exposure is associated with target organ damage in DM and may exacerbate the progression of some chronic complications of DM. This paper reviews relevant epidemiological, in vivo, and in vitro studies to better understand BPA's potential risk associations and pathological mechanisms in several chronic diabetic complications.
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