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Related Experiment Videos

Sodium hyaluronate (Healon) in closed vitrectomy.

J C Folk, A J Packer, T A Weingeist

    Ophthalmic Surgery
    |May 1, 1986
    PubMed
    Summary

    Healon implantation in the vitreous cavity may reduce vitreous hemorrhage in phakic diabetic eyes. However, it can cause increased intraocular pressure in aphakic eyes due to rapid diffusion.

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    Area of Science:

    • Ophthalmology
    • Surgical Innovation
    • Vitreoretinal Surgery

    Background:

    • Pars plana vitrectomy is a common surgical procedure for various retinal conditions.
    • Maintaining tamponade and preventing complications like vitreous hemorrhage are critical post-vitrectomy goals.
    • Healon, a viscoelastic substance, has been used in ophthalmic surgery.

    Purpose of the Study:

    • To evaluate the effects and safety of Healon implantation in the vitreous cavity after pars plana vitrectomy.
    • To assess Healon's impact on intraocular pressure and tamponade in different ocular conditions.
    • To determine Healon's potential role in preventing vitreous hemorrhage in specific patient populations.

    Main Methods:

    • Healon was implanted into the vitreous cavity in 33 eyes post-pars plana vitrectomy.
    • Intraocular pressure and Healon diffusion patterns were observed.
    • Efficacy in managing posterior bleeding was assessed in phakic diabetic eyes.

    Main Results:

    • In aphakic eyes, rapid Healon diffusion into the anterior chamber led to reduced posterior tamponade and elevated intraocular pressure.
    • In phakic diabetic eyes, Healon appeared to mechanically trap hemorrhage from fibrovascular stumps.
    • Healon demonstrated a potential to reduce opacifying vitreous hemorrhage in specific cases.

    Conclusions:

    • Healon's use in the vitreous cavity presents risks of increased intraocular pressure in aphakic eyes.
    • Healon may offer a mechanical tamponade effect, potentially reducing vitreous hemorrhage in phakic diabetic eyes with neovascularization.
    • Careful consideration of patient factors is necessary when using Healon in the vitreous cavity post-vitrectomy.

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