Related Experiment Video
Updated: Aug 5, 2026
10:33
Isolation of Salmonella typhimurium-containing Phagosomes from Macrophages
Published on: October 25, 2017
Stellate maculopathy due to Salmonella typhi. A case report
Summary
This case report details typhoid fever complicated by vision-impairing eye conditions, specifically bilateral chorioretinitis and monolateral stellate maculopathy. It highlights the ocular manifestations of this infectious disease.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Retinal Diseases
Background:
- Typhoid fever, a systemic infection caused by *Salmonella Typhi*, can present with diverse extraintestinal manifestations.
- Ocular complications of typhoid fever are rare but can lead to significant visual impairment.
Observation:
- A case of typhoid fever is presented with unusual ocular findings.
- The patient developed bilateral chorioretinitis and monolateral stellate maculopathy.
Findings:
- Bilateral chorioretinitis, an inflammation of the choroid and retina in both eyes, was observed.
- Monolateral stellate maculopathy, a star-shaped pattern of retinal edema in one eye, was also noted.
- Clinical findings associated with these ocular manifestations are discussed.
Implications:
- This case underscores the importance of ophthalmological evaluation in patients with typhoid fever, especially those with visual symptoms.
- Recognizing these rare ocular complications can aid in timely diagnosis and management, potentially preventing vision loss.
- Further research into the pathogenesis of typhoid retinopathy is warranted.
Related Concept Videos
01:28Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
01:18Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
01:28Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
01:28Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...