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Flow diversion for basilar quadrifurcation aneurysms.

Visish M Srinivasan¹, Jubran H Jubran¹, Henry O Stonnington¹

¹Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.

Journal of Neurointerventional Surgery

|May 30, 2023

Summary

Flow-diverting devices (FDDs) show promise for treating complex basilar quadrifurcation aneurysms. This study found FDDs safe and effective, achieving high occlusion rates with manageable complications in 34 patients.

Keywords:

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Published on: May 11, 2011

Area of Science:

Endovascular neurosurgery
Cerebrovascular disease
Medical devices

Background:

Flow-diverting devices (FDDs) are increasingly used for complex posterior circulation aneurysms.
Limited research exists on FDDs for basilar quadrifurcation aneurysms.
This study addresses the gap in understanding FDD efficacy in this specific anatomical region.

Purpose of the Study:

To evaluate the safety and effectiveness of flow-diverting devices (FDDs) in treating basilar quadrifurcation aneurysms.
To assess technical success, complication rates, and long-term occlusion following FDD treatment.
To determine the potential benefit of FDDs for previously treated aneurysms with residual or recurrent disease.

Main Methods:

Retrospective review of 34 patients treated with FDDs for basilar quadrifurcation aneurysms.
Assessment included aneurysm characteristics, prior treatments, technical success, complications, and occlusion rates.
Follow-up was conducted via angiography to determine long-term aneurysm occlusion.

Main Results:

34 aneurysms (basilar apex, superior cerebellar artery, posterior cerebral artery) were treated.
88% (30/34) achieved complete or near-complete occlusion at a mean follow-up of 6.6 months.
82% experienced no complications; 1 death occurred due to subarachnoid hemorrhage.

Conclusions:

Flow diversion appears to be a safe and effective treatment for basilar quadrifurcation aneurysms.
FDDs may offer significant benefit for recurrent or residual basilar quadrifurcation aneurysms.
Further prospective studies are warranted to confirm these findings.