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E7386 is not a Specific CBP/β-Catenin Antagonist

Yusuke Higuchi1, Cu Nguyen1, Nyam-Osor Chimge1

  • 1Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.

Current Molecular Pharmacology
|May 31, 2023
PubMed
Summary

E7386 is not a specific CBP/β-catenin antagonist, unlike ICG-001 and C82. This study compared E7386 to established antagonists, finding it lacks specific CBP/β-catenin antagonism.

Keywords:
Antagonism.C82CBPE7386ICG-001β-catenin

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