Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

3.4K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimating the global burden of mental health disorders associated with atopic dermatitis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Molecular Biopesticides: An Emerging Frontier for Managing Plant-Parasitic Nematodes.

Journal of agricultural and food chemistry·2026
Same author

Sustainable valorization of artisanal sour buttermilk using nanofiltration and spray drying.

Frontiers in nutrition·2026
Same author

Virulence determinants, antifungal resistance, and genotype-phenotype associations in Candida bloodstream isolates: a three-year surveillance study from Northern India.

Scientific reports·2026
Same author

Photopharmacology in drug discovery: chemical strategies and therapeutic applications of photoswitchable ligands.

Bioorganic chemistry·2026
Same author

Beneficial Microbes in Plant Salinity Stress Responses: Integrating Correlative Evidence With Mechanistic Frameworks.

Physiologia plantarum·2026

Related Experiment Video

Updated: Jul 28, 2025

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.5K

Finite element method-based simulation on bone fracture fixation configuration factors for biodegradable embossed

Girish Chandra1, Ajay Pandey1, Ashish Kumar Singh1

  • 1Department of Mechanical Engineering, Maulana Azad National Institute of Technology, Bhopal, India.

Computer Methods in Biomechanics and Biomedical Engineering
|May 31, 2023
PubMed
Summary

Optimizing biodegradable embossed locking plates (BELCP) with Mg-alloy screws enhances mechanical performance for bone fracture fixation. Minimal bone-plate clearance, a 3mm gap, and 8 screws yield optimal results.

Keywords:
Biodegradablebone fractureembossed structurefinite element methodfixation configuration factorsmagnesium

More Related Videos

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents
06:59

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

13.5K
Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
07:35

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

18.4K

Related Experiment Videos

Last Updated: Jul 28, 2025

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.5K
Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents
06:59

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

13.5K
Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
07:35

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

18.4K

Area of Science:

  • Biomaterials Science
  • Orthopedic Biomechanics
  • Materials Engineering

Background:

  • Biodegradable implants are evolving, but optimizing their mechanical performance for bone fracture fixation remains challenging.
  • Selecting appropriate material and implant design is crucial for maximizing functional outcomes.
  • Fixation configuration factors like bone-plate clearance and screw placement significantly impact implant performance.

Purpose of the Study:

  • To optimize the fixation configuration of biodegradable embossed locking plates (BELCP) using Mg-alloy screws for enhanced mechanical performance in femur fracture fixation.
  • To identify the optimal parameters for bone-plate clearance, interfragmentary gap, screw fixation position, and screw number.
  • To minimize induced stress in the bone-plate construct through simulation.

Main Methods:

  • Finite element method (FEM)-based simulation was employed to analyze stress distribution.
  • Biodegradable embossed locking plates (BELCP) with Mg-alloy screws were simulated on a hollow cylindrical cortical bone model representing femur fragments.
  • Optimization was performed by systematically varying bone-plate clearance, interfragmentary gap, screw fixation position, and screw number under simulated human weight (62 kg).

Main Results:

  • The optimal fixation configuration achieved a minimum induced stress of 41.96 MPa.
  • This optimal configuration demonstrated significant stress reduction compared to maximum stress configurations: 85% less for clearance, 18% for gap, 6% for screw position, and 48% for screw number.
  • The ideal configuration involved minimum bone-plate clearance, a 3 mm interfragmentary gap, and the use of 8 screws, with locking screws initiated from the BELCP center.

Conclusions:

  • Optimized fixation configurations for BELCP with Mg-alloy screws significantly improve mechanical performance in bone fracture fixation.
  • The study identified specific parameters (minimal clearance, 3mm gap, 8 screws) that minimize stress and enhance implant stability.
  • BELCP, when optimized, presents a promising biodegradable implant solution for orthopedic fracture treatment, warranting further experimental validation.