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Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

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Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
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Pulmonary Function Tests01:25

Pulmonary Function Tests

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Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
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Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

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Factors Affecting Pulmonary Ventilation01:19

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Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
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Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
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Physiological Control of Respiration01:23

Physiological Control of Respiration

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Introduction
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Related Experiment Video

Updated: Jul 28, 2025

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
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Pulmonary function following hyperbaric oxygen therapy: A longitudinal observational study.

Connor T A Brenna1, Shawn Khan2, George Djaiani3

  • 1Department of Anesthesiology & Pain Medicine, University of Toronto, Toronto, Ontario, Canada.

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|May 31, 2023
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Summary
This summary is machine-generated.

Modern hyperbaric oxygen therapy (HBOT) protocols do not significantly impact pulmonary function tests. Serial HBOT is safe for patients, even those with pre-existing respiratory conditions, preserving lung function.

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Area of Science:

  • Pulmonary Medicine
  • Hyperbaric Medicine
  • Respiratory Physiology

Background:

  • Pulmonary oxygen toxicity is a known risk of hyperbaric oxygen therapy (HBOT).
  • The impact of contemporary HBOT protocols on lung function remains incompletely understood.
  • Assessing pulmonary function changes during serial HBOT is crucial for patient safety.

Purpose of the Study:

  • To evaluate changes in pulmonary function tests (PFTs) in patients undergoing serial HBOT.
  • To determine if modern HBOT protocols affect lung function over time.
  • To assess HBOT safety in patients with and without pre-existing respiratory conditions.

Main Methods:

  • Prospective data collection from patients undergoing HBOT (2016-2021).
  • Pulmonary function testing (spirometry) performed before and after every 20 HBOT sessions.
  • HBOT administered at 2.0-2.4 ATA with 100% oxygen for 90 minutes, 5 times/week.

Main Results:

  • No significant changes in FEV1, FVC, or FEF25-75 were observed after 20, 40, or 60 HBOT sessions.
  • Subgroup analyses based on respiratory disease, smoking history, or treatment pressure showed no significant pulmonary function changes.
  • Longitudinal spirometry data indicated preserved lung function throughout serial HBOT.

Conclusions:

  • Modern HBOT protocols appear to be unsubstantiated in terms of pulmonary oxygen toxicity risk.
  • Pulmonary function is maintained during serial HBOT, even in patients with conditions like asthma, COPD, and ILD.
  • HBOT can be considered a safe therapeutic option regarding pulmonary function preservation.