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Updated: Jul 28, 2025

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Published on: April 12, 2024
Developing electronic clinical quality measures to assess the cancer diagnostic process
Daniel R Murphy1,2, Andrew J Zimolzak1,2, Divvy K Upadhyay3
1Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
New electronic clinical quality measures (eCQMs) can assess cancer diagnostic performance. These tools help healthcare organizations monitor and improve the evaluation of colorectal and lung cancer red-flag findings.
Area of Science:
- Oncology
- Health Informatics
- Quality Improvement
Background:
- Diagnostic performance measures in cancer care are currently underdeveloped.
- Electronic clinical quality measures (eCQMs) offer a potential solution for quantifying and enhancing cancer diagnostic quality.
Purpose of the Study:
- To develop and implement two eCQMs for assessing the diagnostic evaluation of red-flag findings in colorectal cancer (CRC) and lung cancer.
- To quantify the rates of appropriate follow-up for these red-flag findings using electronic health record data.
Main Methods:
- Developed eCQMs for CRC (based on abnormal stool tests or iron deficiency anemia labs) and lung cancer (based on abnormal chest imaging).
- Utilized electronic health record data from two large healthcare systems to identify abnormal results, appropriate follow-up, and necessary exclusions.
- Conducted clinician reviews of selected patient records to validate eCQM accuracy and categorize reasons for missed diagnostic opportunities.
Main Results:
- The CRC eCQM was implemented at both sites, showing appropriate follow-up rates of 36.0% (VA) and 41.1% (Geisinger).
- The lung cancer eCQM was implemented at the VA, with an appropriate evaluation rate of 61.5%.
- Provider factors were most frequently cited as reasons for missed diagnostic opportunities (84/157 cases).
Conclusions:
- Two eCQMs were successfully implemented to evaluate the diagnostic process for colorectal and lung cancer.
- These eCQMs provide a valuable tool for healthcare organizations to monitor and improve cancer diagnostic performance.
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