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Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

51
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
51
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

48
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
48
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

41
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
41
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

29
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
29
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

46
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
46
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

30
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
30

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Related Experiment Video

Updated: Jul 28, 2025

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

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232

Diabetic Kidney Disease: An Update.

Sonali Gupta1, Mary Dominguez1, Ladan Golestaneh1

  • 1Department of Medicine, Division of Nephrology, Albert Einstein College of Medicine, 3411 Wayne Avenue, 5th Floor, Bronx, NY 10467, USA.

The Medical Clinics of North America
|May 31, 2023
PubMed
Summary

Diabetic kidney disease (DKD) is a leading cause of kidney failure globally. Early recognition and aggressive management in primary care are crucial for preventing and treating this major public health challenge.

Keywords:
AlbuminuriaChronic kidney diseaseDiabetic kidney diseaseDiabetic nephropathyEnd-stage kidney diseaseProteinuria

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Area of Science:

  • Nephrology
  • Endocrinology
  • Public Health

Background:

  • Diabetic kidney disease (DKD) represents a significant global health burden, being the primary cause of chronic kidney disease and end-stage kidney disease.
  • Understanding DKD's pathophysiology and exploring new therapeutic interventions are critical for managing this widespread condition.

Purpose of the Study:

  • To emphasize the critical importance of prioritizing prevention, early detection, referral, and aggressive management of DKD.
  • To highlight the role of primary care in addressing the epidemic of DKD.

Main Methods:

  • Review of current understanding of DKD pathophysiology.
  • Analysis of recent clinical trials for therapeutic interventions.
  • Assessment of DKD management strategies in primary care settings.

Main Results:

  • Recent advancements in understanding DKD mechanisms and new therapeutic trials show promise in combating the disease.
  • Effective management strategies are essential to curb the epidemic of DKD.

Conclusions:

  • DKD is a leading cause of kidney failure worldwide, necessitating urgent attention.
  • Prioritizing prevention, early recognition, referral, and aggressive management of DKD in primary care is paramount.